Searchable abstracts of presentations at key conferences in endocrinology

ea0011p755 | Steroids | ECE2006

Opposite effects of DHEA and DHEAS on chromaffin cells proliferation

Sicard F , Krug AW , Ziegler CG , Sperber S , Ehrhart-Bornstein M , Bornstein SR

Dehydroepiandrosterone (DHEA) and its sulphate ester DHEAS are neurosteroids with potential effects on neurogenesis, neuronal survival and neuronal stem cells proliferation. DHEA is produced by the inner adrenocortical zone, which is in direct contact to the adrenomedullary chromaffin. Unlike the closely related sympathetic neurons, chromaffin cells are able to proliferate throughout the life span. The aim of the present study was to examine in vitro the effect of DHEA ...